Cambridge Healthtech Institute's Fourth Annual In silico Biology Conference "Modeling Systems Biology for Research and Target Prioritization"

In silico biology, the computer aided analysis of biological systems, is a relatively young research area. It first has been coined in the late 1990's and emerged from Theoretical and Computational Biology. As in other fields before, biology experiences an increased use of systems mathematics and computer simulation. With the human genome sequence available, with an exponentially growing number of completely sequenced genomes from various model organisms and with expression and proteomic data at hand, the research paradigm is shifted towards systems analysis and simulation. Computer aided modeling of complex biomolecules and assemblies are already routinely performed. Nowadays, theoretical description and computer simulation of cellular components in larger intra- and inter-cellular networks is of growing importance. Together with classic biological and clinical experiments as well as data from functional genomics, in silico biology will take the leading role in the analysis of biological systems